TirzTom said:One habit that pays for itself: post the method alongside the number.
Saving this. It is the first explanation that did not require me to already understand it.
Clinical perspective, offered as context rather than as advice. The useful move here is to separate what is established from what is widely repeated. Those two sets overlap less than the confident tone of most write-ups suggests, and the second set is where nearly all the disagreement on this board comes from.
Correct me if the detail matters more than I have assumed.
TrialTracker_MD said:The useful move here is to separate what is established from what is widely repeated.
This is my experience too, for whatever a second data point is worth.
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View ResultsTrialTracker_MD said:The useful move here is to separate what is established from what is widely repeated.
Adding the part of the answer the thread has not reached. Albumin binding above 99% is the whole reason weekly dosing works, and it is also why the trough matters more than the peak. People who dose late are not losing a peak, they are letting the trough fall, and the appetite effect tracks the trough.
Correct me if the detail matters more than I have assumed.
One concrete data point for the thread. Practical: whatever you change, write down the date and the reason. In three months the reason is what you will have forgotten, and the reason is what makes the record worth having.