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ForumsOral GLP-1 AgonistsHas anyone dealt with orforglipron phase 2 weight loss data? Page 5

Has anyone dealt with orforglipron phase 2 weight loss data?

BariatricNurseD Thu, Jul 3, 2025 at 12:45 AM 23 replies 1,601 viewsPage 5 of 5
LipidDoc_ATL
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Jul 7, 2025 at 7:57 PM#21
dave_SLC said:
One practical note: write down what you did and when, before you need it.

Agreed on the substance. I would put less weight on the timescale, because two months of anything is not enough to distinguish a trend from a wobble.

19 17rachel_ABQ, traveltech_sara, AttorneyGrant and 16 others
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carl_compliance
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Jul 8, 2025 at 8:16 AM#22
dave_SLC said:
One practical note: write down what you did and when, before you need it.

This answered a question I did not know how to ask.

20 18BrianDallas92, labquiet_amy, emily_PDX and 17 others
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paige_pharma
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Jul 8, 2025 at 8:35 PM#23

Clinical perspective, offered as context rather than as advice. Order of operations matters more than any single choice here: establish a baseline, change one thing, wait long enough for it to express itself, then measure again under the same conditions.

Last edited: Jul 8, 2025 at 9:35 PM
21 19adam_van, Dr.SurgeonPGH, rachel_ABQ and 18 others
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ricardo_MIA
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Jul 9, 2025 at 8:54 AM#24
paige_pharma said:
Order of operations matters more than any single choice here: establish a baseline, change one thing, wait long enough for it to express itself, then…

Same experience, arrived at from the opposite direction. I had assumed I was the exception until I read this.

22 20KetoKyle, CanadaChris, ZaraB_AL and 19 others
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lucas_SP_BR
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Jul 9, 2025 at 9:12 PM#25
paige_pharma said:
Order of operations matters more than any single choice here: establish a baseline, change one thing, wait long enough for it to express itself, then…

There is a second half to this that has not been said yet. Relative and absolute effects need reading together. A 20% relative reduction on a high baseline risk is a large absolute benefit; the same relative figure on a low baseline risk is a small one, and press summaries almost always quote the relative number because it is bigger.

Last edited: Jul 9, 2025 at 11:12 PM
23 21tampaLisa73, KarenAZ_mom, zoe_NC and 20 others
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