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ForumsPublic SquareCost-effectiveness analysis: GLP-1 agonists vs bariatric surgery (ICER 2026)

Cost-effectiveness analysis: GLP-1 agonists vs bariatric surgery (ICER 2026)

HealthEcon_DC Thu, May 28, 2026 at 8:40 PM 15 replies 456 viewsPage 1 of 3
HealthEcon_DC
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May 28, 2026 at 8:40 PM#1

Read the primary source rather than the write-up and the two do not agree, so here is what is actually in it.

This is the one where the stakes are high and the answer is simple: tell the anaesthetist. Delayed gastric emptying means a stomach that is not empty after a standard fast, and that is an aspiration risk under anaesthesia. Current guidance is broadly to hold weekly agents for about a week before an elective procedure and daily agents for a day, but the decision belongs to the anaesthetic team and they can only make it if they know.

Where I think it is weakest: the population was selected and supported in ways a real cohort is not, so I would read the effect size as a ceiling rather than an expectation.

The bit I cannot resolve on my own is how long before a procedure people were told to hold, and whether the interval differs between the weekly and daily agents. I would rather have one careful answer than five confident ones.

Note on sourcing:
Figures above are from the primary publication rather than the press summary. If a number here disagrees with one you have, post yours and we will work out which of us is reading a secondary source.
33 3NeuroNate, JessicaH_TX, KevinCompounds and 30 others
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JessicaH_TX
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May 28, 2026 at 8:56 PM#2
HealthEcon_DC said:
This is the one where the stakes are high and the answer is simple: tell the anaesthetist.

Agreed, and coverage criteria are plan-specific rather than insurer-specific. Two people with the same insurer and different employers have different rules, which is why "my insurer covers it" is not transferable information.

32 2sarah_TO, wendy_avl, jason_paloalto and 29 others
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sarah.morrison
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May 28, 2026 at 9:12 PM#3
HealthEcon_DC said:
This is the one where the stakes are high and the answer is simple: tell the anaesthetist.

This is where I part company with the consensus forming above. Guidance here is not settled and varies by institution, so quoting one society's interval as the rule is misleading. The invariant part is disclosure, not the number of days.

Last edited: May 28, 2026 at 10:12 PM
31 1tony_orlando, Dr.NephBHM_UK, kim_atl_prep and 28 others
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Dr.RheumBOS
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May 28, 2026 at 9:29 PM#4

Taking the question as asked, rather than the general version of it. Denials are usually procedural rather than clinical, and the order that works reflects that. Get the denial reason in writing, because it names the criterion you failed. Then supply the documentation that criterion asks for — usually documented BMI with a comorbidity, or a failed prior therapy. Then appeal, and ask for a peer-to-peer review, because a prescriber talking to a reviewing clinician resolves a large fraction of denials that written appeals do not. Manufacturer copay assistance is separate and applies mainly to commercial insurance, and patient assistance programmes are means-tested rather than a discount.

Last edited: May 29, 2026 at 3:29 AM
30 0lori_vegas, Dr.PulmRoch, maya_sedona and 27 others
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JakeBK_lifts
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May 28, 2026 at 10:55 PM#5
JessicaH_TX said:
Agreed, and coverage criteria are plan-specific rather than insurer-specific.

Can confirm. Same sequence, different timescale.

Last edited: May 29, 2026 at 12:55 AM
29 24DataDave, Dr.GutHealth, amsterdam_pete and 26 others
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