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ForumsOral GLP-1 AgonistsATTAIN-2: orforglipron in T2DM — 12 month update Page 5

ATTAIN-2: orforglipron in T2DM — 12 month update

RetaRick_CA Sat, Aug 16, 2025 at 1:22 PM 35 replies 1,535 viewsPage 5 of 7
carl_compliance
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Nov 2024
Raleigh, NC
Aug 25, 2025 at 5:32 AM#21
quinn_sf said:
If you are going to change something, change one thing and give it long enough to express itself.

I am going to disagree with the direction of travel here. The thread has converged on the tidiest answer rather than the best-supported one, and those are not the same thing.

4 4labquiet_amy, emily_PDX, Dr.SleepRoch and 1 other
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patPC_UT
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Nov 2024
Park City, UT
Aug 26, 2025 at 9:02 AM#22
quinn_sf said:
If you are going to change something, change one thing and give it long enough to express itself.

Fair, and it stops being fair at the extremes. The middle of the range is well understood; the ends are where the honest answer is that nobody knows.

3 3mike.trainer_LA, sarah_nash92, FitDadDave
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LabKate
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Jan 2024
Oregon
Aug 27, 2025 at 12:31 PM#23
quinn_sf said:
If you are going to change something, change one thing and give it long enough to express itself.

Bookmarking. The distinction being drawn above is the one nobody else makes.

Last edited: Aug 27, 2025 at 3:31 PM
2 2Dr.SleepRoch, laura_annarbor
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newstart_MO
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Feb 2026
Springfield, MO
Aug 28, 2025 at 4:00 PM#24

Adding the clinical framing, because it changes how the question reads. Worth answering the question that was asked rather than the one behind it. The narrow version usually has an answer; the broad version usually does not, and answering the broad one is how a thread stops being useful.

1 1TrialNerd_Beth
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BenResearch_OR
Senior Member
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Dec 2023
Oregon
Aug 29, 2025 at 7:28 PM#25
newstart_MO said:
Worth answering the question that was asked rather than the one behind it.

This matches mine closely enough to be worth saying so out loud. Nothing to add that would improve it.

Last edited: Aug 29, 2025 at 8:28 PM
50 0PeptideSynthNJ, Dr.KarenChen, Dr.NateNeph and 47 others
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