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ForumsOral GLP-1 AgonistsSmall molecule vs peptide GLP-1 agonists — anyone have experience? Page 5

Small molecule vs peptide GLP-1 agonists — anyone have experience?

jason_paloalto Thu, Sep 18, 2025 at 10:31 PM 33 replies 1,842 viewsPage 5 of 7
TomFromTexas
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Oct 3, 2025 at 8:23 PM#21
LabKate said:
Keep the original post as written when you update it, and add the correction underneath.

Filing a mild objection. Mild because I might be wrong; an objection because nobody has addressed the case that does not fit. This treats a plausible mechanism as a demonstrated one. Plausible is where you start looking, not where you stop.

50 0PharmD_Rodriguez, julia.endo, JessicaM_2024 and 47 others
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kim_atl_prep
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Aug 2024
Atlanta, GA
Oct 8, 2025 at 6:16 PM#22
LabKate said:
Keep the original post as written when you update it, and add the correction underneath.

Correct, and worth adding that it is reversible. Nothing being described here is a one-way door, which changes how cautious it is reasonable to be.

49 24BiostatsBrad, PeptideSynthNJ, Dr.KarenChen and 46 others
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tampaLisa73
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Oct 2024
Tampa, FL
Oct 13, 2025 at 4:12 PM#23
LabKate said:
Keep the original post as written when you update it, and add the correction underneath.

Saving this. It is the first explanation that did not require me to already understand it. Taking it to my next appointment.

48 23sarah_nash92, FitDadDave, RunnerRach and 45 others
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traveltech_sara
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Jan 2025
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Oct 18, 2025 at 2:11 PM#24

Adding the clinical framing, because it changes how the question reads. Most of what circulates confidently in this community traces back to one summary of one study, and the qualifier was dropped somewhere in the third retelling.

47 22NurseAsh_DET, BenResearch_OR, MikeKY_noInsulin and 44 others
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Dr.PeteFamMed
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Minneapolis, MN
Oct 23, 2025 at 12:13 PM#25
traveltech_sara said:
Most of what circulates confidently in this community traces back to one summary of one study, and the qualifier was dropped somewhere in the third…

Same pattern here, and in the same order.

Last edited: Oct 23, 2025 at 1:13 PM
46 21FranDenver, Dr.BariatricHTX, LindaRN_retired and 43 others
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