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Evidence-based GLP-1 & peptide discussion since 2023
ForumsPsychological & BehavioralGoal weight anxiety — fear of what happens when you arrive

Goal weight anxiety — fear of what happens when you arrive

mel_PDX Mon, May 11, 2026 at 9:21 PM 21 replies 770 viewsPage 1 of 5
mel_PDX
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May 11, 2026 at 9:21 PM#1

My mood has been flatter since about month four and I genuinely cannot work out whether that is the drug, the deficit, or the fact that I no longer have my main coping mechanism.

What would genuinely help is knowing how people separated a drug effect from the ordinary consequences of a large deficit and disrupted sleep, because I cannot.

I would rather have one careful answer than five confident ones.

35 5Dr.NateNeph, PharmD_Rodriguez, julia.endo and 32 others
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NeuroNate
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Dec 2023
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May 11, 2026 at 9:51 PM#2
mel_PDX said:
My mood has been flatter since about month four and I genuinely cannot work out whether that is the drug, the deficit, or the fact that I no longer…

Anxiety increase on mental health: counterintuitive, but losing weight rapidly triggered anxiety for me. Change — even positive change — is stressful. I was anxious about regaining weight.

This is more common than people admit. A therapist who specializes in weight management has been invaluable. Don't neglect the mental health side of this journey.

Last edited: May 12, 2026 at 3:51 AM
34 4wendy_avl, jason_paloalto, Dr.LeslieOBGYN and 31 others
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JennaRN
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May 11, 2026 at 10:21 PM#3
NeuroNate said:
Anxiety increase on mental health: counterintuitive, but losing weight rapidly triggered anxiety for me.
NeuroNate said:
...mental health should only be used alongside therapy...

I'd say therapy should be AVAILABLE to all GLP-1 patients, but requiring it as a precondition for treatment would create an access barrier.

Not everyone can afford therapy. Not everyone needs it. Some people do just fine with medication + lifestyle changes. But for those with emotional eating, body image issues, or disordered eating history, therapy is extremely valuable.

My recommendation: make mental health screening part of the initial assessment, offer therapy as a recommended adjunct, but don't gatekeep medication access behind it.

33 3BiostatsBrad, PeptideSynthNJ, Dr.KarenChen and 30 others
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NauseaFreeNow
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May 11, 2026 at 10:51 PM#4
mel_PDX said:
My mood has been flatter since about month four and I genuinely cannot work out whether that is the drug, the deficit, or the fact that I no longer…

Same experience, arrived at from the opposite direction.

32 2lori_vegas, Dr.PulmRoch, maya_sedona and 29 others
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pete_nash
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Aug 2024
Nashville, TN
May 12, 2026 at 1:34 AM#5

From the other side of the consultation, briefly.

Positive side effects of mental health that surprised me:

  1. Clearer skin — inflammation reduction improved my rosacea
  2. Better sleep — weight loss resolved mild sleep apnea
  3. Improved libido — better body image + improved cardiovascular health
  4. Less joint pain — obvious mechanical benefit
  5. More energy — metabolic improvements across the board

Not everything about GLP-1 therapy is a struggle. There are genuinely wonderful changes too. ✨

Last edited: May 12, 2026 at 7:34 AM
31 1sarah.morrison, NeuroNate, JessicaH_TX and 28 others
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