The psychology of plateaus — mental health during weight loss stalls

Dr.AddMedPHL said:

Genuine plateaus happen too, and the mechanism is metabolic adaptation plus a smaller body.

That reframing is the part I needed. Printing the relevant bit and taking it with me.

From the other side of the consultation, briefly. It helps to ask what evidence would change your mind before you look at any. If nothing would, the discussion is not about evidence, and it is better to say so early than to spend nine posts discovering it.

PharmHunterJen said:

The mental-health dimension is under-measured in the trial literature and the reports here are consistent enough to take seriously.

This is where I part company with the consensus forming above. I would be careful about how confidently the flatness reports get attributed. Rapid weight loss, a large deficit and disrupted sleep produce low mood on their own, and separating that from a drug effect is genuinely hard.

One concrete data point for the thread. If you are going to change something, change one thing and give it long enough to express itself. Four weeks is the usual minimum for anything pharmacological on this board, and two weeks of data has told you almost nothing.

Moderator note: the sourcing question belongs in the vendor section and has been split out. Thread quality here is what the rules are for. Keep it up.