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ForumsOral GLP-1 AgonistsPLEASE just give me a pill already I hate needles so much — my results so far Page 3

PLEASE just give me a pill already I hate needles so much — my results so far

wanda_boise Fri, Jan 16, 2026 at 2:21 PM 14 replies 996 viewsPage 3 of 3
Dr.LipidDallas
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Jan 17, 2026 at 5:21 PM#11
PeptideChemSF said:
There is a difference between no evidence and evidence of no effect, and this subject is one where the two get swapped freely in both directions.

Agreed, and the size of the effect matters as much as its existence. Something real and small gets treated here as though it were real and decisive.

14 14pam_stl, wei_SG, cory_ATX and 11 others
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MarkLI_maint
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Jan 18, 2026 at 2:06 PM#12
BenResearch_OR said:
The absorption variability is real, but it partly averages out over weeks — the steady-state trough is less erratic than any single day would suggest.

That reframing is the part I needed. I will report back once I have actually tried it.

Last edited: Jan 18, 2026 at 7:06 PM
13 13TrialNerd_Beth, HPLC_Greg, LibrarianMeg and 10 others
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carlos_SATX
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Jan 19, 2026 at 10:51 AM#13
PeptideChemSF said:
There is a difference between no evidence and evidence of no effect, and this subject is one where the two get swapped freely in both directions.

This is where I part company with the consensus forming above. Pushing back on the consensus forming here. Consistency is not the same as correctness, and a board that agrees with itself quickly is usually agreeing with the first person who sounded certain.

12 12Dr.BariatricHTX, LindaRN_retired, tommy_boulder and 9 others
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TrialTracker_MD
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Jan 20, 2026 at 7:37 AM#14

One concrete data point for the thread. One habit that pays for itself: post the method alongside the number. A figure without its method cannot be checked, and an unchecked figure is how this community accumulates folklore.

Correct me if the detail matters more than I have assumed.

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mike_mod
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Jan 21, 2026 at 4:23 AM#15

Moderator note: good thread. Keeping it here rather than moving it, because the question is general enough to be useful. Thread quality here is what the rules are for. Keep it up.

Last edited: Jan 21, 2026 at 6:23 AM
10 10PurityPaulOR, MaxMetOK, MounjBrad and 7 others
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