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ForumsOral GLP-1 AgonistsOrforglipron Phase 2 weight loss data — what worked for you? Page 3

Orforglipron Phase 2 weight loss data — what worked for you?

NurseKim_ATL Thu, Jan 22, 2026 at 12:25 PM 13 replies 1,004 viewsPage 3 of 3
LibrarianMeg
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Jan 24, 2026 at 4:18 PM#11
TinaHashiRN said:
The gap between trial results and real-world results is consistent and it is not fraud.

True, and it depends on a baseline nobody has stated. Without knowing where someone started, the same number can be an excellent result or a disappointing one.

48 23Dr.NateNeph, PharmD_Rodriguez, julia.endo and 45 others
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PeptideSynthNJ
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Jan 25, 2026 at 8:31 PM#12
tyler_CSCS said:
The manufacturing argument is the underrated one.

Genuinely useful, thank you. I had the facts and not the framework.

47 22NurseAsh_DET, BenResearch_OR, MikeKY_noInsulin and 44 others
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PeptideChemSF
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Jan 27, 2026 at 12:43 AM#13
TinaHashiRN said:
The gap between trial results and real-world results is consistent and it is not fraud.

I read this differently from TinaHashiRN, on substance rather than tone. I would add the less popular caveat: these trial populations under-represented several groups, older adults and the highest BMI categories among them. The results probably generalise, and "probably" should be stated as an assumption rather than dropped.

Last edited: Jan 27, 2026 at 4:43 AM
46 21FDA_TrackerJim, ricardo_MIA, BrianDallas92 and 43 others
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hank_denver
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Jan 28, 2026 at 4:55 AM#14

The figures, for anyone assembling their own picture. Keep the original post as written when you update it, and add the correction underneath. An edited-away mistake is invisible to the next person who makes it.

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Admin
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Jan 29, 2026 at 9:06 AM#15

Moderator note: a post naming a supplier has been edited. Discuss suppliers in the review sections, not here. Report rather than reply if it drifts again.

44 19PeptideSynthNJ, Dr.KarenChen, Dr.NateNeph and 41 others
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