Clinical perspective, offered as context rather than as advice. There is a difference between no evidence and evidence of no effect, and this subject is one where the two get swapped freely in both directions.
sean_dublin said:There is a difference between no evidence and evidence of no effect, and this subject is one where the two get swapped freely in both directions.
This is my experience too, for whatever a second data point is worth.
sean_dublin said:There is a difference between no evidence and evidence of no effect, and this subject is one where the two get swapped freely in both directions.
Adding the part of the answer the thread has not reached. The mechanism and the magnitude are separate questions. Agreeing that something happens says nothing about whether it happens enough to act on.
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Browse GL BiochemOne concrete data point for the thread. Practical: whatever you change, write down the date and the reason. In three months the reason is what you will have forgotten, and the reason is what makes the record worth having.
Moderator note: leaving this open. It is being argued well and the disagreement is the useful part. No action needed from anybody.