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ForumsPharmacology & MechanismsIncretin effect in healthy vs T2DM — looking for input Page 3

Incretin effect in healthy vs T2DM — looking for input

PedsEndoPhilly Tue, Jun 25, 2024 at 10:31 PM 13 replies 2,056 viewsPage 3 of 3
CryptoCarl
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Jun 26, 2024 at 7:00 PM#11
julia.endo said:
Insulin sensitivity test (HOMA-IR) on glycaemic control — arguably the most important metabolic marker most people aren't tracking: HOMA-IR = (fasting…

That reframing is the part I needed.

Last edited: Jun 26, 2024 at 11:00 PM
1 24CryptoCarl
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Dr.EndoIndy
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Jun 27, 2024 at 2:50 AM#12

From the other side of the consultation, briefly. If two explanations both fit, the useful question is which one predicts something the other does not. That is answerable; arguing about which sounds more plausible is not.

Last edited: Jun 27, 2024 at 5:50 AM
2 0LeilaHI, marcus_mpls
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Dr.AddMedPHL
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Jun 27, 2024 at 10:40 AM#13
Dr.NephBHM_UK said:
PCOS success story with glycaemic control: as someone with polycystic ovary syndrome, this medication has been transformative beyond weight loss.

Filing a mild objection. Mild because I might be wrong; an objection because nobody has addressed the case that does not fit. This treats a plausible mechanism as a demonstrated one. Plausible is where you start looking, not where you stop.

3 1mike.trainer_LA, sarah_nash92, FitDadDave
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DoseLogDan
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Jun 27, 2024 at 6:30 PM#14

The figures, for anyone assembling their own picture. If you are comparing against somebody else’s result, check that you are comparing the same measurement taken the same way. Most of the apparent contradictions in these threads dissolve at that step.

Last edited: Jun 27, 2024 at 7:30 PM
4 2sophie_paris, mel_PDX, Dr.AddMedPHL and 1 other
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mike_mod
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Jun 28, 2024 at 2:20 AM#15

Moderator note: a couple of off-topic posts removed. No action needed from anybody.

Last edited: Jun 28, 2024 at 4:20 AM
5 3PurityPaulOR, MaxMetOK, MounjBrad and 2 others
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