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ForumsOral GLP-1 AgonistsOral sema empty stomach requirement — how strict is it really? Page 3

Oral sema empty stomach requirement — how strict is it really?

mike_nyc Sat, May 23, 2026 at 7:04 AM 23 replies 496 viewsPage 3 of 5
amsterdam_pete
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May 25, 2026 at 7:46 AM#11
Dr.CardioMD said:
Worth answering the question that was asked rather than the one behind it.

Agreed on the substance. I would put less weight on the timescale, because two months of anything is not enough to distinguish a trend from a wobble.

That is the short version; the long version is somebody else's post.

Last edited: May 25, 2026 at 1:46 PM
16 14JakeSmashed95, NauseaFreeNow, SteveThurs and 13 others
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bbq_ray_KC
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May 25, 2026 at 8:05 PM#12
JakeSmashed95 said:
The absorption variability is real, but it partly averages out over weeks — the steady-state trough is less erratic than any single day would suggest.

That reframing is the part I needed.

Last edited: May 25, 2026 at 10:05 PM
17 15MikeFit_NJ, InsuranceTom, WendyG_ATL and 14 others
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MASHdoc_SA
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May 26, 2026 at 8:24 AM#13
Dr.CardioMD said:
Worth answering the question that was asked rather than the one behind it.

Filing a mild objection. Mild because I might be wrong; an objection because nobody has addressed the case that does not fit. This treats a plausible mechanism as a demonstrated one. Plausible is where you start looking, not where you stop.

18 16JennaRN, LabKate, kate.chem and 15 others
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lucas_SP_BR
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May 26, 2026 at 8:42 PM#14

The figures, for anyone assembling their own picture. Keep the original post as written when you update it, and add the correction underneath. An edited-away mistake is invisible to the next person who makes it.

Last edited: May 26, 2026 at 10:42 PM
19 17KarenAZ_mom, zoe_NC, Dr.ObesityLA and 16 others
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mike_mod
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May 27, 2026 at 9:00 AM#15

Moderator note: the sourcing question belongs in the vendor section and has been split out. Tagging this one for the weekly digest.

20 18PurityPaulOR, MaxMetOK, MounjBrad and 17 others
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