NurseAsh_DET said:Receptor pharmacology relevant to the pharmacology: semaglutide is a GLP-1R agonist with a C-18 fatty acid chain that enables albumin binding (>99%),…
No disagreement, though it depends on where somebody is starting from, and this thread has been assuming a starting point nobody stated.
MASHdoc_SA said:The mechanism is more central than most summaries suggest.
This is exactly what I could not find anywhere else. Printing the relevant bit and taking it with me.
NurseAsh_DET said:Receptor pharmacology relevant to the pharmacology: semaglutide is a GLP-1R agonist with a C-18 fatty acid chain that enables albumin binding (>99%),…
This is where I part company with the consensus forming above. This treats a plausible mechanism as a demonstrated one. Plausible is where you start looking, not where you stop.
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View ResultsOne concrete data point for the thread. Keep the original post as written when you update it, and add the correction underneath. An edited-away mistake is invisible to the next person who makes it.
Moderator note: good thread. Keeping it here rather than moving it, because the question is general enough to be useful. Tagging this one for the weekly digest.