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ForumsPharmacology & MechanismsCan someone explain how this drug works like I am not a scientist — what worked for you? Page 3

Can someone explain how this drug works like I am not a scientist — what worked for you?

DebRD_ATL Sat, Feb 22, 2025 at 11:54 AM 16 replies 1,786 viewsPage 3 of 4
JennaRN
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Feb 24, 2025 at 9:11 PM#11
Dr.RenalNash said:
Amycretin (AMY/GLP-1 dual agonist) emerging data relevant to the pharmacology: Phase 1 showed -13.1% body weight at only 12 weeks, the fastest…

That is right for the common case. Whether it is right for the case being asked about depends on a detail that has not been given.

44 17Dr.KarenChen, Dr.NateNeph, PharmD_Rodriguez and 41 others
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tampaLisa73
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Feb 26, 2025 at 8:47 AM#12
pam_columbus said:
The mechanism is more central than most summaries suggest.

Bookmarking. The distinction being drawn above is the one nobody else makes. Sending this to two other people who asked me the same thing last week.

45 18FitDadDave, RunnerRach, TrialNerd_Beth and 42 others
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emma_london
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Feb 27, 2025 at 8:22 PM#13
Dr.RenalNash said:
Amycretin (AMY/GLP-1 dual agonist) emerging data relevant to the pharmacology: Phase 1 showed -13.1% body weight at only 12 weeks, the fastest…

Pushing back on Dr.RenalNash here. I would resist the confidence. Half of what this board was certain about two years ago has since been quietly dropped, and nobody went back to correct the threads.

46 19TomFromTexas, mike.trainer_LA, sarah_nash92 and 43 others
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VendorMark
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Mar 1, 2025 at 7:56 AM#14

Adding the numbers, since they settle part of this. Give anything pharmacological four weeks before you judge it, and give anything measured weekly a four-point rolling average before you call it a trend.

Happy to go further on any of that.

47 20Dr.PeteFamMed, claudia_zurich, nancy_portland and 44 others
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Admin
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Mar 2, 2025 at 7:29 PM#15

Moderator note: a post naming a supplier has been edited. Discuss suppliers in the review sections, not here. No action needed from anybody.

Last edited: Mar 2, 2025 at 11:29 PM
48 21PeptideSynthNJ, Dr.KarenChen, Dr.NateNeph and 45 others
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