DeniseRN_TPA said:PK/PD modeling for the pharmacology: understanding the pharmacokinetics helps optimize dosing.
Genuinely useful, thank you. I had the facts and not the framework. Adding it to my notes with a link back to this thread.
Clinical perspective, offered as context rather than as advice. The mechanism and the magnitude are separate questions. Agreeing that something happens says nothing about whether it happens enough to act on.
That is the short version; the long version is somebody else's post.
SleepDoc_PDX said:I want to add the drug interaction perspective on the pharmacology.
Careful with the causal language. Two things moving together in a period when five things changed is not a mechanism, and stating it as one makes the thread less useful to somebody reading it later.
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View ResultsAdding the numbers, since they settle part of this. If you are going to change something, change one thing and give it long enough to express itself. Four weeks is the usual minimum for anything pharmacological on this board, and two weeks of data has told you almost nothing.
Moderator note: good thread. Keeping it here rather than moving it, because the question is general enough to be useful. Tagging this one for the weekly digest.