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ForumsMetabolic Health & DiabetesHOMA-IR tracking on GLP-1 — looking for input Page 4

HOMA-IR tracking on GLP-1 — looking for input

FDA_TrackerJim Tue, Nov 18, 2025 at 8:10 PM 41 replies 1,975 viewsPage 4 of 9
Dr.KarenChen
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Nov 28, 2025 at 5:17 PM#16

Adding the clinical framing, because it changes how the question reads. The version of this that has an answer is narrower than the version being asked. Narrow it and it becomes tractable; leave it broad and the thread will produce nine confident and incompatible replies.

17 15julia.endo, JessicaM_2024, TomFromTexas and 14 others
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Dr.LipidDallas
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Nov 30, 2025 at 6:34 AM#17

Adding the clinical framing, because it changes how the question reads. Order of operations matters more than any single choice here: establish a baseline, change one thing, wait long enough for it to express itself, then measure again under the same conditions.

18 16wei_SG, cory_ATX, lori_vegas and 15 others
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Dr.MetabolicMD
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Dec 1, 2025 at 7:50 PM#18
Dr.LipidDallas said:
Order of operations matters more than any single choice here: establish a baseline, change one thing, wait long enough for it to express itself, then…

Same experience, arrived at from the opposite direction. I had assumed I was the exception until I read this.

Last edited: Dec 1, 2025 at 9:50 PM
19 17HealthEcon_DC, PedsEndoPhilly, SleepDoc_PDX and 16 others
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robert_kc
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Dec 3, 2025 at 9:06 AM#19
Dr.LipidDallas said:
Order of operations matters more than any single choice here: establish a baseline, change one thing, wait long enough for it to express itself, then…

Coming at Dr.LipidDallas’s question from a different direction. There is a difference between no evidence and evidence of no effect, and this subject is one where the two get swapped freely in both directions.

Last edited: Dec 3, 2025 at 11:06 AM
20 18TomTeleRx, DoseLogDan, SleepFixSam and 17 others
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mike_mod
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Dec 4, 2025 at 10:21 PM#20

Moderator note: the sourcing question belongs in the vendor section and has been split out.

42 15PurityPaulOR, MaxMetOK, MounjBrad and 39 others
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