LindaRN_retired said:Dose-response modeling for tirzepatide: Emax model fitting to the STEP/SURMOUNT dose-finding data shows: Semaglutide: ED50 ≈ 0.6mg, Emax ≈ -18%, Hill…
This is my experience too, for whatever a second data point is worth. Nothing to add that would improve it.
labquiet_amy said:One habit that pays for itself: post the method alongside the number.
This is where I part company with the consensus forming above. This treats a plausible mechanism as a demonstrated one. Plausible is where you start looking, not where you stop.
Correct me if the detail matters more than I have assumed.
labquiet_amy said:One habit that pays for itself: post the method alongside the number.
That holds where the measurement is reliable. Where it is noisy — and a lot of what gets tracked here is noisy — the same reasoning produces confident nonsense.
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Browse GL Biochemlabquiet_amy said:One habit that pays for itself: post the method alongside the number.
Thank you for spelling out the reasoning rather than just the conclusion. Taking it to my next appointment.
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