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ForumsPharmacology & MechanismsCan someone explain how this drug works like I am not a scientist — my results so far Page 3

Can someone explain how this drug works like I am not a scientist — my results so far

SandraNC_45 Fri, Sep 26, 2025 at 6:16 PM 15 replies 1,216 viewsPage 3 of 3
anders_CPH
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Oct 1, 2025 at 11:30 PM#11
Dr.EndoEP said:
Amycretin (AMY/GLP-1 dual agonist) emerging data relevant to the pharmacology: Phase 1 showed -13.1% body weight at only 12 weeks, the fastest…

Agreed, and one caution: a single measurement is not a measurement. Anything that moves day to day needs a trend before it means anything at all.

23 21CryptoCarl, MariaRD, AussieAnna and 20 others
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Dr.EndoIndy
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Oct 3, 2025 at 1:50 AM#12
DataDave said:
The pharmacokinetics explain nearly every practical question asked here.

This answered a question I did not know how to ask. Taking it to my next appointment.

Last edited: Oct 3, 2025 at 4:50 AM
24 22LeilaHI, marcus_mpls, DeniseRN_TPA and 21 others
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Dr.BariatricHTX
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Oct 4, 2025 at 4:09 AM#13
Dr.EndoEP said:
Amycretin (AMY/GLP-1 dual agonist) emerging data relevant to the pharmacology: Phase 1 showed -13.1% body weight at only 12 weeks, the fastest…

I read this differently. The confidence in this thread is running ahead of the evidence, and I would rather the uncertainty were stated than smoothed over because it is unsatisfying.

25 23Dr.EM_Chicago, pete_RVA, CarlaRPh_TPA and 22 others
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dan_philly
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Oct 5, 2025 at 6:28 AM#14

One concrete data point for the thread. Practical: whatever you change, write down the date and the reason. In three months the reason is what you will have forgotten, and the reason is what makes the record worth having.

26 24Dr.CardioMD, EndoResFellow, PharmacoVig_BOS and 23 others
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Admin
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Oct 6, 2025 at 8:46 AM#15

Moderator note: a couple of off-topic posts removed. Thread quality here is what the rules are for. Keep it up.

Last edited: Oct 6, 2025 at 12:46 PM
27 0PeptideSynthNJ, Dr.KarenChen, Dr.NateNeph and 24 others
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