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ForumsPharmacology & MechanismsHas anyone dealt with receptor internalization and recycling? Page 4

Has anyone dealt with receptor internalization and recycling?

steph_laguna Tue, Nov 11, 2025 at 8:29 AM 28 replies 1,190 viewsPage 4 of 6
CanadaChris
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Nov 14, 2025 at 1:55 PM#16
Dr.PathRoch said:
The useful move here is to separate what is established from what is widely repeated.

Second this.

Last edited: Nov 14, 2025 at 7:55 PM
44 17Dr.EM_Chicago, pete_RVA, CarlaRPh_TPA and 41 others
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TomTeleRx
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Nov 14, 2025 at 4:23 PM#17
kate.chem said:
Say what you would expect to see if you were wrong, before you look.

This is exactly what I could not find anywhere else. Printing the relevant bit and taking it with me.

45 18bri_stats, pete_manc_UK, anna.melb_AU and 42 others
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SarahChen_PharmD
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Nov 14, 2025 at 6:51 PM#18

From the other side of the consultation, briefly. The honest answer is that the effect is real, the magnitude is contested, and the individual variation is larger than either. Those three things can all be true at once, and most arguments here are two people holding different parts of that.

If somebody has the primary source to hand I would rather cite it than paraphrase it.

46 19paul_denver, TinaHashiRN, robert_kc and 43 others
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MikeKY_noInsulin
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Nov 14, 2025 at 9:19 PM#19
SarahChen_PharmD said:
The honest answer is that the effect is real, the magnitude is contested, and the individual variation is larger than either.

Same experience, arrived at from the opposite direction. Posting only so the count is not one.

Last edited: Nov 15, 2025 at 12:19 AM
47 20amy_econ_NJ, bbq_ray_KC, oliver_london and 44 others
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Admin
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Nov 14, 2025 at 11:47 PM#20

Moderator note: leaving this open. It is being argued well and the disagreement is the useful part.

19 17PeptideSynthNJ, Dr.KarenChen, Dr.NateNeph and 16 others
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