Dr.CardioMD said:Semaglutide structural biology relevant to the pharmacology: semaglutide is a 31-amino acid peptide with 94% homology to native GLP-1(7-36).
No disagreement, though it depends on where somebody is starting from, and this thread has been assuming a starting point nobody stated.
josh_phd_bmore said:The mechanism is more central than most summaries suggest.
Thank you for spelling out the reasoning rather than just the conclusion. Adding it to my notes with a link back to this thread.
Dr.CardioMD said:Semaglutide structural biology relevant to the pharmacology: semaglutide is a 31-amino acid peptide with 94% homology to native GLP-1(7-36).
I am going to disagree with the direction of travel here. The thread has converged on the tidiest answer rather than the best-supported one, and those are not the same thing.
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