So the drug literally changes your brain?? That is wild

sarah_TO said:

Receptor pharmacology relevant to the pharmacology: semaglutide is a GLP-1R agonist with a C-18 fatty acid chain that enables albumin binding (>99%),…

That is right for the common case. Whether it is right for the case being asked about depends on a detail that has not been given.

If somebody has the primary source to hand I would rather cite it than paraphrase it.

laura_annarbor said:

The mechanism is more central than most summaries suggest.

Saving this. It is the first explanation that did not require me to already understand it.

sarah_TO said:

Receptor pharmacology relevant to the pharmacology: semaglutide is a GLP-1R agonist with a C-18 fatty acid chain that enables albumin binding (>99%),…

Filing a mild objection. Mild because I might be wrong; an objection because nobody has addressed the case that does not fit. The objection nobody has made: this only works if the measurement is doing what we assume it is doing, and that assumption has not been tested here.

One concrete data point for the thread. Say what you would expect to see if you were wrong, before you look. It is a small discipline and it changes what you notice.

Moderator note: a post naming a supplier has been edited. Discuss suppliers in the review sections, not here. No action needed from anybody.