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ForumsPharmacology & MechanismsEnteroendocrine L-cell biology — endogenous GLP-1 secretion and regulation Page 3

Enteroendocrine L-cell biology — endogenous GLP-1 secretion and regulation

Dr.GutHealth Sat, May 23, 2026 at 2:00 AM 20 replies 546 viewsPage 3 of 4
zoe_NC
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May 23, 2026 at 11:33 PM#11
andrew_nyc said:
I want to add the drug interaction perspective on the pharmacology.

This is exactly what I could not find anywhere else. Sending this to two other people who asked me the same thing last week.

43 18Dr.BariatricHTX, LindaRN_retired, tommy_boulder and 40 others
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julia.endo
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May 24, 2026 at 11:56 AM#12

From the other side of the consultation, briefly. The distinction that resolves most of these threads is between what is true on average and what is true for one person. Both are real; they answer different questions and get quoted as if they were the same one.

42 17mark_tokyo, hans_munich, jason_sac26 and 39 others
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KevinCompounds
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May 25, 2026 at 12:20 AM#13
Dr.KarenChen said:
PK/PD modeling for the pharmacology: understanding the pharmacokinetics helps optimize dosing.

Pushing back on Dr.KarenChen here. The counter-case has not been addressed. Somebody upthread described the situation that does not fit, and the thread moved on rather than engaging with it, which is the failure mode this board is supposed to avoid.

41 16MikeKY_noInsulin, Dr.RaviCardio, jennifer_SEA and 38 others
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Dr.NateNeph
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May 25, 2026 at 12:44 PM#14

One concrete data point for the thread. One habit that pays for itself: post the method alongside the number. A figure without its method cannot be checked, and an unchecked figure is how this community accumulates folklore.

Last edited: May 25, 2026 at 2:44 PM
40 15B12Beth, RickReta_CO, PharmHunterJen and 37 others
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mike_mod
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May 26, 2026 at 1:08 AM#15

Moderator note: two posts asking for a source have been merged into one. Please search the thread before asking again. Tagging this one for the weekly digest.

39 14PurityPaulOR, MaxMetOK, MounjBrad and 36 others
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