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ForumsPsychological & BehavioralSleep quality changes on GLP-1 — better or worse?

Sleep quality changes on GLP-1 — better or worse?

Dr.SleepRoch Wed, May 6, 2026 at 9:32 AM 4 replies 439 viewsPage 1 of 1
Dr.SleepRoch
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Apr 2024
Rochester, MN
May 6, 2026 at 9:32 AM#1

Splitting this out of the general thread because the answers kept arriving in ones and twos and nobody could see the shape of it.

My mood has been flatter since about month four and I genuinely cannot work out whether that is the drug, the deficit, or the fact that I no longer have my main coping mechanism.

The bit I cannot resolve on my own is how people separated a drug effect from the ordinary consequences of a large deficit and disrupted sleep, because I cannot.

Roughly, people seem to land in one of these:

  • Held where they were and waited it out
  • Changed one variable and kept everything else fixed
  • Changed several things at once and cannot now attribute the result
  • Stopped and reassessed from a clean baseline

Say which and say why — the why is the useful half.

26 21sarah_TO, wendy_avl, jason_paloalto and 23 others
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COA_Karl
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Jan 2024
Pennsylvania
May 6, 2026 at 9:56 AM#2
Dr.SleepRoch said:
My mood has been flatter since about month four and I genuinely cannot work out whether that is the drug, the deficit, or the fact that I no longer…

Recovering from an eating disorder and using mental health: this is a complex situation and I want to be transparent about it.

I have a history of binge eating disorder. My psychiatrist, therapist, and prescribing doctor all collaborate on my care. The GLP-1 agonist has actually been therapeutic — it removes the biological urgency of binge impulses without relying on restriction.

This is NOT appropriate for all ED patients. Anorexia, bulimia, and restrictive EDs require different approaches. But for BED specifically, the evidence and my personal experience are positive. Always involve your mental health team.

25 20jim_asheville, matt_MKE, Dr.ReproEndo and 22 others
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carl_compliance
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Nov 2024
Raleigh, NC
May 6, 2026 at 10:20 AM#3
COA_Karl said:
Recovering from an eating disorder and using mental health: this is a complex situation and I want to be transparent about it.

Body image adjustment with mental health: I've lost 61 lbs but when I look in the mirror, I still see my old self sometimes. "Phantom fat" is a real phenomenon.

My therapist specializes in body image issues with weight loss patients. She says it can take 12-18 months for your brain's body map to update. In the meantime: take progress photos (your eyes lie but cameras don't), try on old clothes, and be patient with yourself.

24 19ricardo_MIA, BrianDallas92, labquiet_amy and 21 others
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kevin_tulsa
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Jun 2024
Tulsa, OK
May 6, 2026 at 10:44 AM#4
Dr.SleepRoch said:
My mood has been flatter since about month four and I genuinely cannot work out whether that is the drug, the deficit, or the fact that I no longer…

This is my experience too, for whatever a second data point is worth. I had assumed I was the exception until I read this.

Last edited: May 6, 2026 at 12:44 PM
23 18quinn_sf, NurseLeah_Nash, gary_naperville and 20 others
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SarahChen_PharmD
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May 6, 2026 at 12:57 PM#5

From the other side of the consultation, briefly.

One year anniversary on mental health — reflections:

What I wish I'd known: the side effects are temporary, the benefits compound over time, protein is more important than I thought, and the mental health aspect needs as much attention as the physical.

What surprised me: how much my relationship with food changed, the cascade of health improvements beyond weight, and how supportive this community is.

What I'd do differently: start therapy earlier, prioritize resistance training from day 1, and stop comparing my progress to others. Everyone's journey is unique.

22 17robert_kc, dan_philly, MeganSA_TX and 19 others
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